健康环保材料课题组负责人

    陈仕国，男，深圳大学教授，博士生导师，硕士生导师，2005年博士毕业于中山大学高分子化学与物理专业，同年7月入职深圳大学，2006年晋升为副教授，2012年晋升为教授。

    广东省高等学校“千百十人才培养工程”省级培养对象，深圳市高层次专业人才，深圳大学优秀青年教师（“荔园优青”），南山区生物医用高分子材料和安全性评价重点实验室主任。

    全国质量监管重点产品检验方法标准化技术委员会能源检验方法专业工作组委员，中国化学会会员，中国抗菌协会会员，中国纺织工程学会会员，深圳市分析测试协会化工测试专业委员会副主任委员，深圳市政府重大行政决策咨询专家。

    获广东省科技进步二等奖2项，获广东高校科技成果转化路演大赛三等奖（第五名）,广东省优秀科技成果1项，10余项科技成果已转化应用。

    本方向长期接收有机化学，化工，高分子，药物化学，制药工程、生物材料、染整工程等相关研究背景的博士毕业生前来本课题组从事博后研究。

   欢迎勤奋好学，勇于探索，具有化学、高分子、生物医学、食品科学、纺织工程等相关背景，并对生命健康和节能环保高分子材料有浓厚兴趣的同学报考本课题组的研究生。

    联系方式：E-mail:csg@szu.edu.cn, QQ:1975188168

    ResearcherID: J-3076-2014; ORCID ID:http://orcid.org/0000-0002-5338-690X

健康材料课题组主要研究领域（兴趣）：

1. 生物医用高分子材料设计制备、构效关系及应用

 1）高分子仿生神经移植物、高分子药物载体、脑靶向药物载体等生物医用高分子材料的结构设计、 合成、结构与性能关系及应用； 

 2）抗菌抗病毒高分子材料的结构设计、 合成、结构与性能关系及应用；

 3）高分子材料（棉纺织品，羊毛，涤纶，粘胶纤维，纤维素，壳聚糖,PP无纺布等）的表面抗菌抗病毒除螨功能改性、结构与性能关系及应用；

 4）多功能纳米材料的设计制备、结构与性能关系、生物效应及其安全性评价。

2.建筑防腐防霉材料的结构设计、合成及构效关系

3.其他功能高分子材料

 1）新型结构色材料的设计制备、构效关系及应用

 2）多功能涂料的设计制备及应用

部分第一作者和通讯作者学术论文

40) Yihong Cao^#, Ziyu Yang^#, Jiahui Ou, Guangcheng Chu, Yuanwang Wang^*, Shiguo Chen^*.Ultra-transparent, hard and antibacterial coating with pendent quaternary pyridine salt. Progress in Organic Coatings, 2023:107369.

39)  Wanjing Zou^#, Jingwei Gu^#, Jianna Li, Yuanfeng Wang^*, Shiguo Chen^*. Tailorable antibacterial and cytotoxic chitosan derivatives by introducing quaternary ammonium salt and sulfobetaine. International Journal of Biological Macromolecules,2022,218:992-1001.

38）Jinhao Xie,Yuanfeng Wang^*, Shiguo Chen^*. Textile-based asymmetric hierarchical systems for constant hydrovoltaic electricity generation. Chemical Engineering Journal, 2022, 431:133236.

37）Sheng Ding, Yihong Cao, Fengting Huang, Yuanfeng Wang^*, Jianna Li, Shiguo Chen^*. Spontaneous polarization induced electrostatic charge in washable electret compsoites fabrics for reusable air filtering applications. Composites Science and Technology, 2022, 217:109093.

36) Liling Li, Yongling Mai, Yuanfeng Wang*, Shiguo Chen*. Stretchable unidirectional liquid-transporting membrane with antibacterial and biocompatible features based on chitosan derivative and composite nanofibers. Carbohydrate Polymers，2022, 276:118703.

35）Shu Wang^#，Jianna Li^#,YiHong Cao Jingwei Gu,YuanFeng Wang^*, Shiguo Chen^*. Non-leaching, rapid bactericidal and biocompatible polyester fabrics finished with benzophenone terminated N-halamine. Advanced Fiber Materials, 2022,4:119-128.

34) Zhuocheng Zhang, Yihong Cao, Jingwei Gu, Jianna Li, Yuanfeng Wang^*,Shiguo Chen^*.Giant persistent antibacterial and biocompatible polyester fabrics for anti-mold food packaging. Materials Today Chemistry, 2021, 22:100571.

33）Fengting Huang; Yanhong Weng, Yanxuan Lin, Xingcai Zhang, Yuanfeng Wang^*,Shiguo Chen^*. Wetting-enhanced structural color for convenient and reversible encryption of optical information. ACS Applied Materials & Interfaces,2021,13:42276-42286.

32) Sheng Ding, Yuanfeng Wang^*, Jianna Li, Shiguo Chen^*.Progress  and prospects in chitosan derivatives: Modification strategies and medical applications. Journal of Materials Science and Technology, 2021,89:209-224.  

31) Qiupeng Lin, Jun Huang, Junlong Yang, Yi Huang, Yifan Zhang, Yueji Wang, Jianmin Zhang, Yan Wang, Linlin Yuan, Minkun Cai, Xingyu Hou, Weixing Zhang, Shiguo Chen*, Chuanfei Guo*. Confirmation for highly sensitive flexible iontronic pressure for fingertrip pulse monitoring.Advanced Healthcare Materials, 2020, 9:1023.

30) Teng Zhang^#, Huali Yu^#, Jianna Li, Haibo Song,Shu Wang, Zhuocheng Zhang, Shiguo Chen^*.Green-light-triggered antimicrobial cotton fabric for wastewater disinfection. Materials Today Physics, 2020, 15:100254.

29) Fang Ding, lingpu Zhang, Hao Chen, haiqin Song^*, Shiguo Chen^*, Haihua Xiao^*. Enhancing chemotherapy efficacy of platinum prodrug nanoparticles and inhibiting cancer metastasis via targeting iron homeostasis.Nanoscale Horizons, 2020,5:999-1015.

28) Yihong Cao, Jingwei Gu, ShuWang, Zhuocheng Zhang, Huali Yu, Jianna Li^*, Shiguo Chen^*. Guanidine-functionalized cotton fabrics for achieving permanent antibacterial activity without compromising their physicochemical properties and cytocompatibility. Cellulose, 2020,27:6027-6036.

27) Teng Zhang^#, Jingwe Gu^#, XiangYu Liu, Dengshuai Wei, Huiling Zhou, Haihua Xiao, Zhuocheng Zhang, Huali Yu, Shiguo Chen^*. Bactericidal and antifouling electrospun PVA nanofibers modified with a quaternary ammonium salt and zwitterionic sulfopropylbetaine. Materials Science & Engineering C, 2020,111:110855.

26) Zhigang Chen, Xiaoxu Kang,Yixin Wu, Haihua Xiao, Xuzi Cai, Shihou Sheng*, Xuefeng Wang*, Shiguo Chen*. A mitochondria targeting artesunate prodrug loaded nanoparticle exerting anticancer activity via iron-mediated generation of reactive oxygen species. Chemical Communications, 2019,55(33):4781-4784.  

25) Shiguo Chen*, Shaobo Zhang, Massimiliano Galluzzi, Fan Li, Xingcai Zhang*, Xinghui Yang, Xiangyu Liu, Xiaohua Cai, Xingli Zhu, Bing Du, Jianna Li, Peng Huang*. Insight into multifunctional polyester fabrics finished by one-step eco-friendly strategy. Chemical Engineering Journal，2019,358:634-642. ESI 高引论文

24）Wanjing Zou, Yuxiang Chen, Xingcai Zhang, Jianna Li, Leming Sun, Zifan Gui, Bing Du, Shiguo Chen*. Cytocompatible chitosan based multi-network hydrogels with good antimicrobial, cell anti-adhesive and mechanical properties. Carbohydrate Polymers, 2018, 202:246-257.

23）Jingwei Gu, Lingjun Yuan,Ze Zhang, Xinhui Yang, Junxuan Luo, Zifan Gui, Shiguo Chen*. Non-leaching bactericidal cotton fabrics with well-preserved physical properties, no skin irritation and no toxicity. Cellulose, 2018, 25:5415-5426.  

22) Guowei Wang, Lusha Peng, Bin Yu, Shiguo Chen*, Zaochuan Ge^*, Hiroshi Uyama. Hierarchically porous sponge for oily water treatment: facile fabrication by combination of particulate templates and thermally induced phase separation method. Journal of Industrial and Engineering Chemistry, 2018, 62:192-196.  

21）Shaobo Zhang, Xinghui Yang, Bing Tang, Lingjun Yuan, Kui Wang, Xiangyu Liu, Xingli Zhu, Jianna Li, Zaochuan Ge, Shiguo Chen^*. New insights into synergistic antimicrobial and antifouling cotton fabrics via dually finished with quaternary ammonium salt and zwitterionic sulfobetaine.Chemical Engineering Journal， 2018，336:123-132.  ESI 高引论文

20) Yuqing Niu, Florian J. Stadler, Tao He, Xingcai Zhang, Yingjie Yu^*,Shiguo Chen^*. Smart multifunctional polyurethane microcapsules for the quick release of anticancer drugs in BGC 823 and HeLa tumor cells. Journal of Materials Chemistry B, 2017, 5:9477-9481.

19) Yuqing Niu, Tao He, Jun Song, Siping Chen, Xiangyu Liu, Zhigang Chen, Yingjie Yu^*, Shiguo Chen^*. A new AIE multi-block polyurethane copolymer material for subcellular microfilaments imaging in living cells. Chemical Communications, 2017,53:7541-7544.  

18) Yuqing Niu, Florian J. Stadler, Jun Song, Siping Chen, Shiguo Chen^*. Facile fabrication of polyurethane microcapsules carriers for tracing cellular internalization and intracellular pH-triggered drug release. Colloids and Surfaces B: Biointerfaces, 2017,153:160-167.  

17) Xiangyu Liu, Yuqing Niu, Shiguo Chen^*. Rapid hemostatic and mild polyurethane urea foam wound dressing for promoting wound healing. Materials Science & Engineering C, 2017,71:289-297.

16) Shiguo Chen^*, Lingjun Yuan, Qingqing Li, Jianna Li, Xingli Zhu, Yongguang Jiang, Ou Sha, Xinhui Yang, John H. Xin, Jiangxin Wang^*, Stader J. Florian and Peng Huang^*. Durable antibacterial and nonfouling cotton textiles with enhanced comfort via zwitterionic sulfopropylbetaine coating. Small，2016,12(26): 3516-3521.

15) Yuxiang Chen, Jianna Li, Qingqing Li, Yuanyuan Shen, Zaochuan Ge, Wenwen Zhang, Shiguo Chen^*. Enhanced water-solubility, antibacterial activity and biocompatibility upon introducing sulfobetaine and quaternary ammonium to chitosan. Carbohydrate Polymers, 2016,143:246-253.  

14) Dan Zhu, Honghao Cheng, Jianna Li, Wenwen Zhang, Yuanyuan Shen, Shaojun Chen, Zaochuan Ge, Shiguo Chen*. Enhanced water-solubility and antibacterial activity of novel chitosan derivatives modified with quaternary phosphonium salt. Materials Science and Engineering C, 2016 61:79-84. ESI高引论文.  

13) Shiguo Chen*,Yujuan Guo, Huanqiong Zhong, Jianna Li*, Shaojun Chen, Zaochuan Ge, Jiaoning Tang. Synergistic antibacterial mechanism and coating application of copper/ titanium dioxide nanoparticles. Chemical Engineering Journal, 2014, 256:238-246.  

12) Shaojun Chen, Hongming Yuan, Zaochuan Ge, Shiguo Chen^*, Haitao Zhuo^*, Jianhong Liu. Insights into liquid-crystalline shape-memory polyurethane composites based on an amorphous reversible phase and hexadecyloxybenzoic acid.Journal of Materials Chemistry C, 2014,2(6), 1041-1049.

11) Peixin Zhang^*, Yanyi Wang, Yang Wang, Xiangzhong Ren, Kun Liu, Shiguo Chen^*. Electrochemical lithiation and delithiation performance of SnSb–Ag/carbon nanonube composites for lithium-ion batteries.Journal of Power Sources, 2013, 233(1):166-173.

10) Dongdong Yao, Yujuan Guo, Shiguo Chen^*, Jiaoning Tang, Yongming Chen*. Shaped core/shell polymer nanoobjects with high antibacterial activities via block copolymer microphase separation. Polymer, 2013,54(14):3485-3491.

9) Shiguo Chen*, Yujuan Guo, Shaojun Chen Zaochuan Ge, Haipeng Yang, Jiaoning Tang. Fabrication of Cu/TiO₂ nanocomposite: Toward an enhanced antibacterial performance in the absence of light. Materials Letters, 2012, 83:154-157.

8) Shiguo Chen^*，Yujuan Guo, Shaojun Chen，Huimin Yu，Zaochuan Ge，Xuan Zhang，Peixin Zhang, Jiaoning Tang^*. Facile preparation and synergistic antibacterial effect of three-component Cu/TiO₂/CS nanoparticle.Journal of Materials Chemistry, 2012,22(18):9092-9099.

7)  Shiguo Chen^*, Shaojun Chen, Song Jiang, Yangmiao Mo, Junxuan Luo, Jiaoning Tang, Zaochuan Ge. Study of zwitterionic sulfobetaine containing functional siloxane for antibacterial materials. Colloids and Surfaces B: Biointerfaces, 2011,85(2):323-329.  

6) Shiguo Chen^*, Shao jun Chen, Song Jiang, Meiling Xiong, Junxuan Luo, Jiaoning Tang, Zaochuan Ge. Environmentally friendly antibacterial cotton textiles finished with siloxane sulfopropylbetaine. ACS Applied Materials & Interfaces，2011,3(4):1154-1162.

5) Shiguo Chen, Xianlei Hu, Mingqiu Zhang^*, Minzhi Rong, Qiang Zheng. Relationships between organic vapor adsorption behaviors and gas sensitivity of carbon black filled waterborne polyurethane composites. Sensors and Actuators B:Chemical, 2006,119(1):110-117.

4) Shiguo Chen, Jiwen Hu, Mingqiu Zhang^*, Minzhi Rong, Qiang Zhang. Time dependent percolation of carbon black filled polymer composites in response to solvent vapor. Journal of Materials Science, 2005.40(8):2065-2068.  

3) Shiguo Chen, Jiwen Hu, Mingqiu Zhang*, Minzhi Rong, Qiang Zheng. Improvement of gas sensing performance of carbon black/waterborne polyurethane composites: effect of cross linking treatment. Sensors and Actuators B:Chemical, 2006.113(1):361-369.  

2) Shiguo Chen, Jiwen Hu, Mingqiu Zhang^*, Minzhi Rong. Effects of temperature and vapor pressure on the gas sensing behavior of carbon black filled polyurethane composites. Sensors and Actuators B: Chemical, 2005,105 (2):187-193.  

1) Shiguo Chen, Jiwen Hu, Mingqiu Zhang^*, MingWei Li; Minzhi Rong. Gas sensitivity of carbon black/waterborne polyurethane composites.Carbon, 2004,42(3):645-651.    

申请与授权发明专利情况：

 申请国际专利10余项，已授权6项美国发明专利，申请中国发明专利20余项，已授权10项，10余项成果已实现转化。

外文专著：

1）Wei Zeng, Shiguo Chen, Bin Zhao, MinZhi Rong, Mingqiu Zhang^*. Physical properties and applications of polymer nanocomposites (Edited by S.C.Tjong and Y.W. Mai), Part 4 Applications. Gas sensing conductive polymer nanocomposites filled with carbon black nanoparticles. 2010, P690-722., Woodhead Publishing.

 承担国家级科研项目7项，省级科研项目4项，市级项目多项.

01）"十四五"国家重点研发计划项目课题：基于增材制造（3D打印）与静电纺丝技术“内芯外鞘”仿生神经移植物研发(No.2021YFC2400802),2021.11-2026.11. 在研，课题负责人.

02）"十四五"国家重点研发计划项目子课题：基于相分离技术引导神经趋化生长的“生物供能”仿生神经移植物研发(No.2021YFC2400803),2021.11-2026.11. 在研，子课题负责人.

03) 国家自然科学基金（面上项目）:涤纶纺织品的后整理及其持久抗菌防螨和吸湿亲水性研究(No.51773117)，2018.1- 2021.12. 结题，项目负责人.

04）国家自然科学基金（面上项目）：新型壳聚糖衍生物及其协同抗菌活性、抗菌机理和生物相容性研究(No.51573097),2016.1-2019.12.结题，项目负责人.

05）国家自然科学基金（青年基金）: 新型超亲水高分子抗菌剂的分子设计、合成及作用机制研究(No.50803037),2009.1-2011.12. 结题，项目负责人.

06）国家自然科学基金（面上项目）：多孔纳米氧化镁的无模板水热合成与掺杂离子作用机制研究（No.51174138）.2012.01-2015.12. 结题，核心参与（第二）.

07）国家自然科学基金（青年基金）:超分子液晶形状记忆聚氨酯的制备及结构性能研究（No.21104045). 2012.01-2015.12. 结题， 核心成员（第三）.

08）广东省科技计划项目：新型环境友好抗菌整理剂的设计合成及在棉织物整理中的应用研究（No.2015A010105033），2015.1-2017.12. 结题.，项目负责人 

09）广东省自然科学基金：甜菜碱改性壳聚糖及其协同抗菌机理研究(No.S2013010013056)，2013.10-2015.10，结题，项目负责人. 

10）广东省自然科学基金：高效持久聚有机硅氧烷季铵盐类超亲水抗菌剂的研制(No.2008211)，2008.10-2010.10, 结题，项目负责人.

11）广东省科技计划项目（产学研）：高效除螨复合纳米滤网的研制及新型空气净化器的开发（No.2014B090901041）. 结题，核心成员（第二）.

12）深圳市科技攻关项目：长效广谱抗菌抗病毒车辆内饰件水性涂层关键技术研发（No.JSGG20201102153801005）.2021.1-2022.12,在研，合作单位负责人.

13）深圳市科技攻关项目：多功能抗菌抗病毒防护材料关键技术研发（No.JSGG20201102153801001）.2021.1-2022.12,在研，合作单位负责人.

14）深圳市科技研发资金项目(深港创新圈):安全持久抗菌整理剂的设计合成及其在纺织品上的应用研究(No.SGLH20120926161415782), 2013.8-2015.7，结题，项目负责人.

15）深圳市科技计划项目：壳聚糖的高效抗菌和生物相容性改性基础研究(No.JCYJ20120613090936342)，2012.10-2014.10，结题，项目负责人.

16）深圳市南山区创新机构组建资助项目：南山区生物医用高分子材料和安全性评价重点实验室(No.KC2014ZDZJ0001A),2015.1-2017.12,结题，项目负责人. 

17）深圳市政府发展研究中心重大研究课题：新材料产业创新资源全球分布调查研究，2013.12-2014.8，结题，项目负责人.

18）深圳大学交叉学科团队项目：健康与节能环保材料. 2018.1-2022.12，在研.项目负责人.  

获奖情况(含指导学生竞赛)：

1）陈仕国，苏勇，桂子凡，邹小芬等. 多功能健康防护纺织整理剂关键技术及应用. 2020年度广东省科技进步二等奖.颁发单位：广东省人民政府，2021/05.

2）刘志刚.冉不鑫，终南山，陈仕国等. 尘螨过敏性疾病的基础及防控技术应用.2015年度广东省科技进步二等奖,颁发单位：广东省人民政府，2016/02.

3）陈仕国. 广东省高等学校“千百十人才培养工程 ”省级培养对象. 颁发单位：广东省教育厅，2014/11.

4）陈仕国，苏勇，邹小芬，桂子凡等. 持久抗菌柔软防水整理剂及产业化，广东省优秀科技成果，颁发单位：广东省科技厅，2020/07.

5）陈仕国，邝勇军，张卓成，曹怡红. 广东高校科技成功转化路演大赛初创组三等奖. 颁发单位：广东省教育厅.2019/12.

6)陈仕国. 深圳大学突出贡献奖. 颁发单位：深圳大学，2022/9.

7）陈仕国. 深圳大学突出贡献奖. 颁发单位：深圳大学，2021/12.

8）陈仕国. 深圳市高层次专业人才（地方级），颁发单位：深圳市人事局，2009/04.

9）陈仕国. 深圳大学优秀青年教师培养计划（首届“荔园优青”），颁发单位：深圳大学. 2012/12-2022/04.(连续滚动三期）.

10）陈仕国. 深圳大学新锐研究生导师. 颁发单位：深圳大学，2020/09.

11）郭玉娟. Cu/TiO2和壳聚糖多组分抗菌材料的协同抗菌效应研究（导师：陈仕国）. 广东省优秀硕士学位论文，颁发单位：广东省教育厅，2014/11.

12）郭玉娟. 低成本高抗菌纳米抗菌剂的研制(导师：陈仕国）.第十二届“挑战杯”广东省大学生课外学术科技作品竞赛一等奖. 颁发单位：广东省教育厅， 人事厅，共青团广东省委，2013/06.

13）王锦涛，莫杨妙，熊美玲等. 新型反应性有机抗菌剂的制备及其应用研究（导师:陈仕国）. 第十一届“挑战杯”广东省大学生课外学术科技作品竞赛二等奖，颁发单位：广东省教育厅，人事厅，共青团广东省委，2011/05.

14）郭玉娟，钟焕琼，陈予想. 高效抗菌纳米材料的研制及抗菌活性研究（导师：陈仕国）. 2014中国“华为杯”大学生新材料创新设计大赛三等奖，2014/0

15) 郭玉娟. Cu/TiO2和壳聚糖多组分抗菌材料的协同抗菌效应研究（导师：陈仕国）. 深圳大学优秀硕士学位论文.颁发单位：深圳大学， 2013/12.

16）袁红明. 形状记忆聚氨酯液晶复合物研究（导师：陈仕国）. 深圳大学优秀硕士学位论文，颁发单位：深圳大学，2014/12.