王东职务: 职称:教授 办公电话:0755-86713941 EMAIL:wangd@szu.edu.cn |
王东,博士,特聘教授。获得国家优秀青年、广东省杰出青年等基金项目。现任深圳大学AIE研究中心主任(执行),中国化学会分子聚集发光专业委员会委员,Wiley旗下Luminescence期刊主编,Aggregate、Exploration、《发光学报》、VIEW、BMEMat、Biosensors、SmartMat期刊编委/青年编委。
教育背景:
2011.9-2014.9 法国波尔多大学 (Bordeaux University, France),博士
2008.9-2013.6 兰州大学,博士
2004.9-2008.6 兰州大学,本科
工作经历:
2018.4-今 深圳大学材料学院,深圳大学AIE研究中心
2015.12-2018.3 香港科技大学(HKUST),博士后
2014.10-2015.10 加拿大多伦多大学(Toronto University, Canada),博士后
联系方式:
电话:0755-86713941
地址:深圳大学西丽校区材料学院521室
E-mail:wangd@szu.edu.cn
深圳大学AIE研究中心长期招收博士后,欢迎具有有机合成、生物材料、光物理等相关研究背景的博士加入。也欢迎硕士生和本科生加入课题组。
学术研究:
研究方向为:聚集诱导发光(AIE)材料的开发、机理研究,及其在传感、生物成像和疾病诊疗等方面的应用。
以第一/通讯作者在Nat. Nanotechnol.、Matter、Nat. Commun.、J. Am. Chem. Soc.、Adv. Mater.、Angew Chem. Int. Ed.、Chem. Rev.、Chem. Soc. Rev.、Acc. Chem. Res.等期刊上发表SCI论文200余篇,22篇论文入选“ESI高被引论文”,论文共被引用14500余次,H指数为61。申请专利30余项,授权25项。
代表性科研论文
2024年
Bin Li, Wei Wang, Lu Zhao, Yunxia Wu, Xiaoxue Li, Dingyuan Yan, Qiuxia Gao,Yan Yan, Jie Zhang, Yi Feng, Judun Zheng, Bowen Su, Jiamei Wang, Huanhuan Wang, Lingjie He, Yunlong Zhang, Mingliang Pan, Dong Wang*, Ben Zhong Tang*, Yuhui Liao*, Pre-Activated Macrophage-Mimicking Nanoparticles for Lesion-Pathogen Dual Targeting and NIR-IIb Imaging-Guided Photothermal Therapy of Tuberculosis, Nat. Nanotechnol. 2024, accepted (ESI高被引)
Yansheng Zhai, Xinyu Zhang, Dingyuan Yan, Kailu Tian, Zhe Zhang, Yan Huang, Yu-Hsuan Tsai, Xi Yang, Dong Wang, Wen Sun, Gang Li*, Global profiling of functional histidines in live cells using small molecule photosensitizer and chemical probe relay labeling, Nat. Chem. 2024, accepted
Dingyuan Yan, Zheng Li, Michelle M. S. Lee, Ben Zhong Tang, Dong Wang,* NIR-II AIEgens for Infectious Diseases Phototheranostics, Angew. Chem. Int. Ed. 2024, doi: 10.1002/anie.202414259
Jiangao Li, Niu Niu, Deliang Wang, Jun Zhu, Xue Li, Qiyu Kong, Ben Zhong Tang, Dong Wang*, As Aggregation-Induced Emission Meets with Noncovalent Conformational Locks: Subtly Regulating NIR-II Molecules for Multimodal Imaging-Navigated Synergistic Therapies, Angew. Chem. Int. Ed. 2024, doi: 10.1002/anie.202413219
Dingyuan Yan, Zhijun Zhang, Jianyu Zhang, Xue Li, Qian Wu, Yixiong Gui, Jun Zhu, Miaomiao Kang, Xiaohui Chen, Ben Zhong Tang, and Dong Wang*, An All-rounder for NIR-II Phototheranostics: Well-Tailored 1064 nm Excitable Molecule for Photothermal Combating Orthotopic Breast Cancer, Angew. Chem. Int. Ed. 2024, accepted
Wei Wang, Bin Li, Yunxia Wu, Mengjun Li, Dong Wang*, Chenguang Shen*, Ben Zhong Tang*, Yuhui Liao*, et al. Macrophages-derived biomimetic nanoparticles for light driven theranostics towards Monkeypox, Matter, 2024, accepted (ESI高被引)
Yixiong Gui, Yuanwei Wang, Deliang Wang, Yi Qin, Guangjie Song, Dingyuan Yan,* Ben Zhong Tang* and Dong Wang*, Thiophene π-Bridge Manipulation of NIR-II AIEgens for Multimodal Tumor Phototheranostics, Angew. Chem. Int. Ed. 2024, accepted
Benzhao He‡, Ying Li‡, Meng Li, Miaomiao Kang, Xinyue Liu, Jiachang Huang*, Dong Wang*, Jacky W. Y. Lam*, Ben Zhong Tang, Pyridinium-Yne Click Polymerization: A Facile Strategy toward Functional Poly(Vinylpyridinium Salt)s with Multidrug-Resistant Bacteria Killing Ability, Angew. Chem. Int. Ed. 2024, accepted
Caifa You#, Yiqi Zhu#, Jun Zhu, Zixuan Xu, Qian Liu, Lei Wang, Weijie Zhang*, Jianquan Hou*, Dong Wang*, and Ben Zhong Tang*, Strength in Numbers: A Giant NIR-II AIEgen with One-for-All Phototheranostic Features for Exceptional Orthotopic Bladder Cancer Treatment, Angew. Chem. Int. Ed. 2024, accepted
Meijiao Zhao#, Miaomiao Kang#, Jingru Wang#, Ronghua Yang#, Xiaoping Zhong#, Qihu Xie, Sitong Zhou,Zhijun Zhang, Judun Zheng, Yixun Zhang, Shuang Guo, Weiqiang Lin, Jialin Huang, Genghong Guo, YuFu, Bin Li, Zhijin Fan, Xipeng Li, Dong Wang*, Xu Chen*, Ben Zhong Tang*, and Yuhui Liao*, Stem Cell-Derived Nanovesicles Embedded in Double-Layered Hydrogel for Programmed ROS Regulation and Comprehensive Tissue Regeneration, Adv. Mater. 2024, doi: 10.1002/adma.202401369
Wenguang Zhang,# Miaomiao Kang,# Xue Li, Yinzhen Pan, Zhuorong Li, Yibin Zhang, Changrui Liao, Gaixia Xu, Zhijun Zhang,* Ben Zhong Tang,* Zhourui Xu,* Dong Wang*, Fiber Optic-Mediated Type I Photodynamic Therapy of Brain Glioblastoma Based on an Aggregation-Induced Emission Photosensitizer, Adv. Mater. 2024, doi: 10.1002/adma.202410142
Zheng Li, Ben Zhong Tang,* Dong Wang*, Bioinspired AIE Nanomedicine: A Burgeoning Technology for Fluorescence Bioimaging and Phototheranostics, Adv. Mater. 2024, doi: 10.1002/adma.202406047
Wenguang Zhang,# Miaomiao Kang,# Xue Li, Hao Yang, Zhijun Zhang,* Zhuorong Li, Yibin Zhang, Miaozhuang Fan, Changrui Liao, Chengbo Liu, Gaixia Xu,* Dong Wang,* Zhourui Xu,* Ben Zhong Tang*, Interstitial Optical Fiber-Mediated Multimodal Phototheranostics Based on an Aggregation-Induced NIR-II Emission Luminogen for Orthotopic Breast Cancer Treatment, Adv. Mater. 2024, doi: 10.1002/adma.202406474
Huanhuan Wang,‡ Bin Li,‡ Yan Sun,‡ Qiang Ma,‡ Yi Feng, Yan Yan, Wei Wang, Bowen Shu, Jundun Zheng, Yanqiu Wu, Yunlong Zhang, Xiaoxue Li, Qiuxia Gao, Jiamei Wang, Shuo Sang, Fei Ma, Yue Jia, Dingyuan Yan,* Dong Wang,* Xiaoming Zou,* and Yuhui Liao*, NIR-II AIE Luminogen-Based Erythrocyte-Like Nanoparticles with Granuloma-Targeting and Self-Oxygenation Characteristics for Combined Phototherapy of Tuberculosis, Adv. Mater. 2024, accepted
Zhourui Xu,# Xue Li,# Zengming Yang, Zhijun Zhang, Yibin Zhang, Miaozhuang Fan, Yuying Zeng, Miaomiao Kang,* Yuanyuan Shen,* Dong Wang,* Gaixia Xu, Ben Zhong Tang*, An NIR-II Two-Photon Excitable AIE Photosensitizer for Precise and Efficient Treatment of Orthotopic Small-Size Glioblastoma, Adv. Mater. 2024, accepted
Yuanwei Wang, Ke Ma, Miaomiao Kang, Dingyuan Yan, Niu Niu, Saisai Yan, Panpan Sun, Luzhi Zhang, Lijie Sun, Dong Wang*, Hui Tan*, Ben Zhong Tang*, A New Era of Cancer Phototherapy: Mechanisms and Applications, Chem. Soc. Rev. 2024, accepted
2023年
Kaiyuan Wang, Yang Li, Xia Wang, Zhijun Zhang, Liping Cao, Xiaoyuan Fan, Bin Wan, Fengxiang Liu, Xuanbo Zhang, Zhonggui He, Yingtang Zhou*, Dong Wang*, Jin Sun*, Xiaoyuan Chen*, Nat. Commun. 2023, in press (ESI高被引)
Shanliang Song, Yue Zhao, Miaomiao Kang, Fei Zhang, Qian Wu, Niu Niu, Hao Yang, Haifei Wen, Shuang Fu, Xue Li, Zhijun Zhang*, Ben Zhong Tang*, and Dong Wang*, An NIR-II Excitable AIE Small Molecule with Multimodal Phototheranostic Features for Orthotopic Breast Cancer Treatment, Adv. Mater. 2023, 2309748
Jie Cui, Fei Zhang, Dingyuan Yan, Ting Han, Lei Wang, Dong Wang* and Ben Zhong Tang*, "Trojan Horse" Phototheranostics: Fine-Engineering NIR-II AIEgen Camouflaged by Cancer Cell Membrane for Homologous-Targeting Multimodal Imaging-Guided Phototherapy, Adv. Mater. 2023, doi: 10.1002/adma.202302639
Bin Li, Wei Wang, Lu Zhao, Mengjun Li, Dingyuan Yan, Xiaoxue Li, Jie Zhang, Qiuxia Gao, Yi Feng, Judun Zheng, Bowen Shu, Yan Yan, Jiamei Wang, Huanhuan Wang, Lingjie He, Yunxia Wu, Sitong Zhou, Xinchi Qin, Wentao Chen, Kaizhen Qiu, Chenguang Shen,* Dong Wang,* Ben Zhong Tang,* Yuhui Liao*, Aggregation-Induced Emission-Based Macrophage-Like Nanoparticles for Targeted Photothermal Therapy And Virus Transmission Blockage in Monkeypox, Adv. Mater. 2023, 2305378
Dan Li, Xiaohui Chen, Wenbin Dai, Qiao Jin, Dong Wang*, Jian Ji*, Ben Zhong Tang*, Photo-triggered Cascade Therapy: A NIR-II AIE Luminogen Collaborating with Nitric Oxide Facilitates Efficient Collagen Depletion for Boosting Pancreatic Cancer Phototheranostics, Adv. Mater. 2023, 2306476
Shiping Yang, Jianyu Zhang, Zhijun Zhang,* Weilin Xu, Miaomiao Kang, Xue Li, Dingyuan Yan, Ryan T. K. Kwok, Jianwei Sun, Jacky W. Y. Lam, Dong Wang,* and Ben Zhong Tang*, More Is Better: Acceptor Engineering for Constructing NIR-II AIEgens to Boost Multimodality Phototheranostics, J. Am. Chem. Soc. 2023, in press
Dingyuan Yan, Yue Huang, Jianyu Zhang, Qian Wu, Guangjie Song, Jian Ji, Qiao Jin,* Dong Wang,* Ben Zhong Tang*, Adding Flying Wings: Butterfly-shaped NIR-II AIEgens with Multiple Molecular Rotors for Photothermal Combating of Bacterial Biofilms, J. Am. Chem. Soc. 2023, in press
Jiangao Li, Miaomiao Kang,* Zhijun Zhang, Xue Li, Weilin Xu, Dong Wang,* Xike Gao* and Ben Zhong Tang*, Synchronously Manipulating Absorption and Extinction Coefficient of Semiconducting Polymers via Precise Dual-Acceptor Engineering for NIR-II Excited Photothermal Theranostics, Angew. Chem. Int. Ed. 2023, in press (ESI高被引)
Yi Qin, Qing-Hui Ling, Yu-Te Wang, Yi-Xiong Hu, Lianrui Hu, Xiaoli Zhao, Dong Wang,* Hai-Bo Yang, Lin Xu,* and Ben Zhong Tang*, Construction of Covalent Organic Cages with Aggregation-Induced Emission Characteristics from Metallacages for Mimicking Light-Harvesting Antenna, Angew. Chem. Int. Ed.2023, e202308210
2022年
Zhijun Zhang, Miaomiao Kang, Hui Tan, Nan Song, Meng Li, Peihong Xiao, Dingyuan Yan, Liping Zhang, Dong Wang,* and Ben Zhong Tang*, Fast-growing field of photo-driven theranostics based on aggregation-induced emission, Chem. Soc. Rev. 2022, in press (Emerging Investigators 2022) (ESI高被引)
Shanliang Song,# Yajun Wang,# Yue Zhao, Wenbin Huang, Fei Zhang, Shoujun Zhu,* Qian Wu, Shuang Fu, Ben Zhong Tang,* Dong Wang,* Molecular Engineering of AIE Luminogens for NIR-II/IIb Bioimaging and Surgical Navigation of Lymph Nodes, Matter, 2022, in press
Yi Qin,# Xiaohui Chen,# Yixiong Gui, Heng Wang, Ben Zhong Tang,* and Dong Wang,* A Self-Assembled Metallacage with Second Near-Infrared Aggregation-Induced Emission for Enhanced Multimodal Theranostics. J. Am. Chem. Soc. 2022, in press (ESI高被引)
Peihong Xiao,# Wei Xie,# Jianyu Zhang, Qian Wu, Zipeng Shen, Chenqi Guo, Yi Wu, Fubing Wang,* Ben Zhong Tang,* and Dong Wang*, De Novo Design of Reversibly pH-Switchable NIR-II Aggregation-Induced Emission Luminogens for Efficient Phototheranostics of Patient-Derived Tumor Xenograft, J. Am. Chem. Soc. 2022, in press
Kang Wang,# Saisai Yan,# Ting Han,* Qian Wu, Neng Yan, Miaomiao Kang, Jinyin Ge, Dong Wang,* Ben Zhong Tang*, Cascade C‒H-Activated Polyannulations toward Ring-Fused Heteroaromatic Polymers for Intracellular pH Mapping and Cancer Cell Killing, J. Am. Chem. Soc. 2022, in press
Jianxing Wang,‡ Jie Li,‡ Meng Li, Ke Ma, Dong Wang,* Lei Su,* Xueji Zhang,* Ben Zhong Tang*, Nanolab in a Cell: Crystallization-Induced in situ Self-Assembly for Cancer Theranostic Amplification, J. Am. Chem. Soc. 2022, in press
Dingyuan Yan# , Tingting Li # , Yilin Yang, Niu Niu, Deliang Wang, Jinyin Ge, Lei Wang, Ruiping Zhang*, Dong Wang* and Ben Zhong Tang*, A Water-soluble AIEgen for Noninvasive Diagnosis of Kidney Fibrosis via SWIR Fluorescence and Photoacoustic Imaging, Adv. Mater. 2022, doi: 10.1002/adma.202206643
Haoxuan Li,* Bingqi Jin, Yuanwei Wang, Bingyao Deng, Dong Wang,* Ben Zhong Tang*, As Fiber Meets with AIE: Opening a Wonderland for Smart Flexible Materials, Adv. Mater. 2022, doi: 10.1002/adma.202210085
Dingyuan Yan,# Miao Wang,# Qian Wu, Niu Niu, Meng Li, Ruixiang Song, Jie Rao, Miaomiao Kang, Zhijun Zhang, Feifan Zhou,* Dong Wang* and Ben Zhong Tang*, Multimodal Imaging-Guided Photothermal Immunotherapy Based on a Versatile NIR-II Aggregation-Induced Emission Luminogen, Angew. Chem. Int. Ed. 2022, doi:10.1002/anie.202202614
Yifan Wu#, Jiangao Li#, Zipeng Shen, Deliang Wang, Ruihua Dong, Jiangjiang Zhang, Yinzhen Pan, Ying Li*, Dong Wang* and Ben Zhong Tang*, Double-pronged Antimicrobial Agents based on a Donor-π-Acceptor Type Aggregation-Induced Emission Luminogen, Angew. Chem. Int. Ed. 2022, in press
Benzhao He, Jiachang Huang,* Jianyu Zhang, Herman H. Y. Sung, Jacky W. Y. Lam, Zhijun Zhang, Saisai Yan, Dong Wang,* Jing Zhang,* and Ben Zhong Tang*, Novel Quinolizine AIE System: Visualization of Molecular Motion and Elaborate Tailoring for Biological Application, Angew. Chem. Int. Ed. 2022, doi: 10.1002/anie.202117709
2021年
Qian Wu, Junkai Liu, Youmei Li, Michelle M. S. Lee, Lianrui Hu, Ying Li, Panwang Zhou, Dong Wang,* and Ben Zhong Tang*, Janus luminogens with bended intramolecular charge transfer: towards 2 molecular transistor and brain imaging, Matter 2021, doi: 10.1016/j.matt.2021.08.002
Yuanwei Wang, Youmei Li, Zhijun Zhang, Lei Wang, Dong Wang*, Ben Zhong Tang*, Triple-Jump Photodynamic Theranostics: MnO2 Combined Upconversion Nanoplatforms Involving Type-I Photosensitizer with Aggregation-Induced Emission Characteristics for Potent Cancer Treatment, Adv. Mater. 2021, doi: 10.1002/adma.202103748.
Haoxuan Li, Wei Zhu, Meng Li, Ying Li*, Ryan T. K. Kwok, Jacky W. Y. Lam, Lei Wang, Dong Wang*, Ben Zhong Tang*, Side Area-Assisted 3D Evaporator with Antibiofouling Function for Ultra-Efficient Solar Steam Generation, Adv. Mater. 2021, doi: 10.1002/adma.202102258.
Jie Li, Jianxing Wang, Jianyu Zhang, Ting Han*, Xiyao Hu, Michelle M. S. Lee, Dong Wang*, Ben Zhong Tang*, A Facile Strategy of Boosting Photothermal Conversion Efficiency through State Transformation for Cancer Therapy, Adv. Mater. 2021, doi: 10.1002/adma.202105999
Dingyuan Yan,# Wei Xie,# Jianyu Zhang,Lei Wang, Dong Wang* and Ben Zhong Tang* Donor/π-Bridge Manipulation for Constructing a Stable NIR-II Aggregation-Induced Emission Luminogen with Balanced Photo-theranostic Performance, Angew Chem. Int. Ed. 2021, in press (ESI高被引)
Wenhan Xu, Dong Wang,* Ben Zhong Tang*, NIR-II AIEgens: A Win-Win Integration towards Bioapplications. Angew Chem. Int. Ed. 2021, 60, 7476. (ESI高被引)
2020年
Jie Li, Jianxing Wang, Haoxuan Li, Nan Song, Dong Wang,* Ben Zhong Tang*,Supramolecular materials based on AIE luminogens (AIEgens): constructions and applications, Chem. Soc. Rev. 2020, 49, 1144. (ESI高被引)
Zhijun Zhang, Wenhan Xu, Miaomiao Kang, Haifei Wen, Heng Guo, Pengfei Zhang, Lei Xi, Kai Li, Lei Wang,Dong Wang,* Ben Zhong Tang*, An All-Round Athlete on the Track of Phototheranostics: Subtly Regulate the Balance between Radiative and Non-Radiative Decays for Multimodal Imaging-Guided Synergistic Therapy, Adv. Mater. 2020, doi: 10.1002/adma.202003210. (ESI高被引)
Jiachang Huang, Benzhao He, Zhijun Zhang, Youmei Li, Miaomiao Kang, Yuanwei Wang, Kai Li, Dong Wang,* Ben Zhong Tang*,Aggregation-Induced Emission Luminogens-Married 2D Black Phosphorus Nanosheets for Highly Efficient Multimodal Theranostics, Adv. Mater. 2020, 2003382.
Nan Song, Zhijun Zhang, Peiying Liu, Ying-Wei Yang, Lei Wang, Dong Wang,* Ben Zhong Tang*, Nanomaterials with Supramolecular Assembly Based on AIE Luminogens for Theranostic Applications, Adv. Mater. 2020, 32, 2004208.
Haoxuan Li#, Haifei Wen#, Zhijun Zhang, Nan Song, Ryan T. K. Kwok, Jacky W. Y. Lam, Lei Wang, Dong Wang,* Ben Zhong Tang*, Reverse Thinking of Aggregation-Induced Emission Principle: Amplifying Molecular Motions to Boost Photothermal Efficiency of Nanofibers, Angew Chem. Int. Ed.2020, 10.1002/anie.202008292.
Jie Li, Kang Peng, Youmei Li, Jianxing Wang, Jianbin Huang, Yun Yan,* Dong Wang,* Ben Zhong Tang*, Exosome-Mimetic Supramolecular Vesicles with Reversible and Controllable Fusion and Fission, Angew Chem. Int. Ed. 2020, 59, 21510.
Wenhan Xu, Michelle M. S. Lee, Jing-Jun Nie, Zhihan Zhang, Ryan T. K. Kwok, Jacky W. Y. Lam, Fu-Jian Xu, Dong Wang,* Ben Zhong Tang,* Three-Pronged Attack by Homologous Far-red/NIR AIEgens to Achieve "1+1+1>3" Synergistic Enhanced Photodynamic Therapy, Angew Chem. Int. Ed. 2020, 59, 9610. (ESI高被引)
Dingyuan Yan, Qian Wu, Dong Wang,* Ben Zhong Tang*, Innovative Synthetic Protocols for Aggregation-Induced Emission Luminogens: Recent Advances and Prospects, Angew Chem. Int. Ed. 2020, DOI: 10.1002/anie.202006191. (ESI高被引)
2019年
Dong Wang,* Ben Zhong Tang*, AIE Luminogens for Activity-Based Sensing,
Miaomiao Kang, Chengcheng Zhou, Shuangmei Wu, Bingran Yu, Zhijun Zhang, Nan Song, Michelle Mei Suet Lee, Wenhan XU, Fu-Jian Xu, Dong Wang,* Lei Wang,* and Ben Zhong Tang*, Evaluation of Structure-Function Relationships of Aggregation-Induced Emission Luminogens for Simultaneous Dual Applications of Specific Discrimination and Efficient Photodynamic Killing of Gram-Positive Bacteria,
Dong Wang,* Michelle M. S. Lee, Wenhan Xu, Guogang Shan, Xianglong Hu, Xiaoyan Zheng,Ryan T. K. Kwok, Jacky W. Y. Lam, Ben Zhong Tang*,
2018年
Dong Wang,* Michelle M. S. Lee, Guogang Shan, Ryan T. K. Kwok, Jacky W. Y. Lam, Huifang Su, Yuchen Cai, Ben Zhong Tang*, Adv. Mater. 2018, 1802105. (ESI高被引)
1. 国家自然科学基金委-优秀青年科学基金项目
2. 国家自然科学基金面上项目
3. 国家自然科学青年基金
4. 广东省杰出青年基金项目
5. 深圳市海外高层次人才启动项目
6. 深圳市自然科学基金基础面上项目
7. 高分子合成与功能构造教育部重点实验室开放基金
1. 广东省科学技术奖-青年科技创新奖
2. 深圳市青年科技奖
3. 深圳市自然科学奖二等奖(第一完成人)
4. Biomaterials Science新锐科学家
5. Science China Chemistry新锐科学家
6. Chemical Society Reviews新锐科学家
7. Materials Chemistry Frontiers新锐科学家
8. 深圳大学2021届,2022届百篇优秀本科毕业论文(设计)指导教师
9. 深圳大学荔园优青
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